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+Compared with mouse thymocytes, mouse ES cells comprise greater levels of whole genomic H3K4me3 and have higher H3K4me3 occupancy on the promoter of the pluripotent gene Oct4 46 In settlement with this, global decreases in H3K4me3 ranges happen during retinoic acid (RA)-induced [differentiation](https://sellasiss.com/author/5ce0fdf28ab7b68e/) of mouse ES cells forty seven In addition, there are dynamic changes in H3K4me3 profiles at particular units of genes during ES cell differentiation.
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